SEOUL,South Korea,Nov. 25,2024 -- J INTS BIO announced research findings on its innovative brain tumor treatment,'JIN-001,' developed in collaboration with MD Anderson Cancer Center,at the 2024 Society of Neuro-Oncology (SNO) Annual Meeting in Texas,USA. MD Anderson is a globally renowned cancer research institution,and J INTS BIO has partnered with it since 2021 to advance this groundbreaking therapy.

JIN-001: Aiming to Revolutionize Brain Tumor Treatment

'JIN-001' targets glioblastoma (GBM) cells by significantly enhancing the efficacy of radiation therapy and chemotherapy. As a selective inhibitor of HSP90 (Heat Shock Protein 90),its primary advantage lies in its ability to cross the blood-brain barrier (BBB),which typically hinders therapeutic agents from reaching the brain. While the BBB serves as a protective mechanism for the brain,it also presents a major obstacle for drug delivery. JIN-001 overcomes this limitation,directly attacking brain tumors and addressing the low permeability issue of existing drugs.

The study also highlighted that JIN-001 demonstrated promising results when combined with standard therapies such as Radiation Therapy and Temozolomide,effectively suppressing tumor cell growth and inducing apoptosis (programmed cell death).

JIN-001: Pioneering Future Clinical Developments

Based on these promising findings,J INTS BIO plans to accelerate preclinical trials for JIN-001. The company intends to incorporate CRISPR gene-editing technology to identify the functional roles of specific genetic factors in treatment resistance,paving the way for precision medicine strategies. CRISPR-based techniques allow targeted modulation of gene expression,helping to predict and better understand tumor responses.

J INTS BIO is also advancing plans to commercialize JIN-001 through partnerships with global pharmaceutical companies,aiming to bring faster and more effective treatments to brain tumor patients. Furthermore,the potential applications of JIN-001 are being explored in treating a wide range of cancers beyond brain tumors,providing new hope for cancer patients worldwide.

JIN-001 represents a groundbreaking innovation that transcends the limitations of existing therapies,offering new treatment opportunities and hope for improved survival and quality of life for brain tumor patients.